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Properties of gold films sputtered under different conditions onto borosilicate glass substrate were studied. Targeting sarcoplasmic reticulum calcium ATPase by gene therapy. To meet current challenges in agriculture, genome editing using sequence-specific nucleases (SSNs) is a powerful tool for basic and applied plant biology research. Moxifloxacin, a fluoroquinolone antibiotic associated with QT prolongation, has been recommended as a positive control by regulatory authorities to evaluate the sensitivity of both clinical and preclinical studies to detect small but significant increases in QT interval measurements.

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A total of 3200 participants aged 15-50 years were enumerated and examined using the Rapid Assessment of Refractive Error (RARE) protocol. Strains of S.pneumoniae contain PBP-1A, PBP-2B and PBP-2X proteins. We identified several metabolic pathways underlying altered protein expression. A computerised method of analysing fetal heart rate and uterine activity using a simple algorithm has demonstrated a capability to predict fetal acidosis at the time of delivery. Vulnerable children should be a key focus of healthcare interventions if inequities are to be addressed.

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High-resolution three-dimensional diffusion-weighted imaging of middle ear cholesteatoma at 3.0 T MRI: usefulness of 3D turbo field-echo with diffusion-sensitized driven-equilibrium preparation (TFE-DSDE) compared to single-shot echo-planar imaging. Pain with activity was the strongest predictor of participant satisfaction.

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Overall, clinical benefit was not obtained by mRH in patients with clinical stage I/II endometrial carcinomas. Short tandem repeat (STR) analysis of casework samples with low DNA content include those resulting from the transfer of epithelial cells from the skin to an object (e.g., cells on a water bottle, or brim of a cap), blood spatter stains, and small bone and tissue fragments.

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A quasi-experimental, pre- and post-test questionnaire study of men at 14 workplace and leisure sites across two primary care trusts was undertaken: ten experimental sites received the intervention and four acted as a control. Previous studies have shown that treatment of these cells with tetanus toxoid or anti-human IgG reagents can inhibit this in vitro antibody synthesis. C57BL/6 mice infected with the helminth Schistosoma mansoni develop small hepatic granulomas around parasite eggs, but concomitant immunization with soluble schistosome egg Ags (SEA) in CFA (SEA/CFA) causes marked exacerbation of the lesions in a Th1-dominated environment characterized by high levels of IFN-gamma.

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GGA (300 mg/kg, i.d.) could prevent the decreases of the total amount of gastric glycoproteins in the mucous layer plus gastric mucosa. Because our patient was in the hospital when the iliac artery ruptured, prompt diagnosis and treatment were possible. Organization of oculistic and orthoptic medical services in communes larger cities, and in various important communes, with special reference to Bergamo Barium sulfate aspiration: Severe chemical pneumonia induced by a massive reflux of contrast medium during small bowel barium enema. Proliferative activity of human solid tumors evaluated by thymidine labeling index and primer-dependent alpha-DNA polymerase.

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Our objective is to identify steps in designing an effective simulation program, curricula, and scenario using available evidence and drawing on experience. Recognition of tumor-suppressive miRNA-regulated molecular targets provides new insights into the potential mechanisms of cervical SCC oncogenesis and metastasis and suggests novel therapeutic strategies for treatment of this disease.

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The effect of pronation and inclination on the measurement of the hallucal distal metatarsal articular set angle. Clinical evaluation of pravastatin in the treatment of type II hyperlipidemia in patients with non-insulin-dependent diabetes mellitus. None of the currently available agents has been proven to prevent regurgitation.

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This association is probably not fortuitous but, rather, may represent the most extreme form of a spectrum of left-sided heart anomalies seen in patients with Turner syndrome. By using a mammalian genetic replacement strategy, we were able to assemble fluorescently tagged Sec8 into the exocyst complex, which was shown to be functional by biochemical, trafficking, and morphological criteria. Fetal venous, intracardiac, and arterial blood flow measurements in intrauterine growth retardation: relationship with fetal blood gases. Although hyperglycemia is a key therapeutic focus in the management of patients with type 2 diabetes mellitus (T2DM), many patients experience sub-optimal glycemic control.

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The rising ventilatory cost of bicycle exercise in the seventh decade: a longitudinal study of nine healthy men. Observations from these procedures as they have been applied to a review of the safety of acid-suppressing medications will be discussed. Urine cytology immediately after flexible cystoscopy correlates well with results of urine cytology before cystoscopy.

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We utilised a mu suppression method in our action-listening study to detect involuntary motor coactivation when pianists passively listened to piano melodies. In this study, we examined ICAM-1 expression by primary rat microglia and found that only IFN-gamma and IFN-gamma/LPS enhance ICAM-1 gene expression. Activation of lymphocytes by a thiol-derivatized nucleoside: characterization of cellular parameters and responsive subpopulations. The findings suggest that m-calpain may act at an early phase of CIA as a matrix proteinase and take part in the destruction of articular cartilage or activate other destructive enzymes. Production of medium chain length fatty alcohols from glucose in Escherichia coli.

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We report a case of spurious hyperchloraemia, elevated total carbon dioxide and negative anion gap 9 days following a voiding cystourethrogram (VCU) in a patient with bladder exstrophy and obstructive uropathy. Moxalactam, cefoxitin, and piperacillin demonstrated the best pharmacokinetic performances for the third-generation cephalosporin, second-generation cephalosporin, and newer penicillin groups, respectively. DNA double-strand breaks and micronuclei in human blood lymphocytes after repeated whole body exposures to 7T Magnetic Resonance Imaging. In diabetic patients the carbachol induced SAR response and the histamine induced itching sensation were significantly reduced in stage III of PNP.

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The elevation in the hepatoma RNA polymerase I activity resulted from both an increase in the number of transcriptionally active enzyme molecules and an increase in the specific activity of the enzyme as a result of phosphorylation. Effect of secretin and caerulein on the absorption of water, electrolytes and glucose from the jejunum of dogs. This procedure facilitates the conversion of a useless, mutilated hand into a well-functioning one in a single operation. Inappropriate exposure of gametes and/or products of conception to nutritional imbalance alters critical metabolic set points in the offspring and increases propensity to disease. Clinical significance of diabetes mellitus on detrusor functionality on stress urinary incontinent women without bladder outlet obstruction.

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In cathepsin S-deficient mouse pancreatic cancers, processing of these cathepsin substrates is highly reduced, pointing to an essential role of cathepsins in extracellular shedding. Overall, our data support a role of p120 phosphorylation as a marker and mediator of tumor transformation. Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection.

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Recently, we demonstrated that regulation of the Gtl2-Dio3 noncoding RNA locus is dependent on the MEF2 transcription factor in cardiac muscle, and that two of its encoded miRNAs, miR-410 and miR-495, induce robust cardiomyocyte proliferation. Alkaliphilic Bacteria with Impact on Industrial Applications, Concepts of Early Life Forms, and Bioenergetics of ATP Synthesis. Between January 1990 and December 2001, 670 patients underwent 920 minor amputations (interphalangeal, ray, or transmetatarsal) on 747 limbs. Pasteurized whole milk is an attractive oral contrast agent, providing good GI distension, mural visualization, and GI landmark discrimination. Organometallic coordination polymers generated from bent Bis(acetylenylphenyl)oxadiazole ligands and Ag(I) salts.

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Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor. CD2 or CD28 stimulation, but not CD3/TCR stimulation, induces Dok phosphorylation. A broad spectrum of microbes including mycoplasma, bacteria, fungi, and viruses are the causative agents of cell culture contamination. These results suggest that at high cell density, the switching of binding of transcription factors from ETS1 to ELK3 occurs at a specific binding site of the PAI-1 promoter, leading to the cell-density dependent suppression of PAI-1 expression.

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Consumer direction is a service delivery model that shifts decision-making from agencies to the individuals they serve. The proliferation of clonal cytotoxic T-cells or natural killer cells has been observed after dasatinib treatment in small studies of patients with chronic myeloid leukemia (CML).

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Pseudomonas aeruginosa and Candida albicans are two pathogens frequently encountered in the intensive care unit microbial community. The major thiol-disulfide couple of reduced glutathione (GSH) and oxidized glutathione is a key regulator of major transcriptional pathways regulating aseptic inflammation and recovery of skeletal muscle after aseptic injury. Positron emission tomography is a useful technique in the presurgical differentiation between benign and malignant peripheral nerve sheath tumors.

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Vascular Surgery Unit, Department of Surgery, University of Perugia, Perugia, Italy. The effect of parathyroidectomy on insulin sensitivity in patients with primary hyperparathyroidism - an never ending story? Comparative effectiveness of natural and synthetic bone grafts in oral and maxillofacial surgery prior to insertion of dental implants: Systematic review and network meta-analysis of parallel and cluster randomized controlled trials. The abnormal karyotypes always appeared with normal mitosis in single or clonal cells.

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The blood serum content of cholesterol, phospholipids, proteins and lipoproteins of patients with diabetes mellitus during treatment with sulfanyl-urea derivatives Dental utilization of active duty/previous active duty US military: a cross-sectional analysis of the 2010 Behavior and Risk Surveillance Survey. The HiMAT, which assesses higher-level mobility requirements of people with TBI for return to pre-accident social, leisure and sporting activities, is a uni-dimensional and discriminative scale for quantifying therapy outcomes. Youth who report risky substance use and who have a familial history of substance use disorders (SUDs) are at increased risk for developing SUDs themselves later in life. Lifelong susceptibility to acoustic trauma: changing patterns of cochlear damage over the life span of the mouse.

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Lipid peroxidation and vitamin E in red blood cells and plasma in hemodialysis patients under rhEPO treatment. Taken together, these findings establish a role for p18 in regulating the activity of the RNA polymerase II elongation complex, and they bring to light a function for a UbH domain protein in transcriptional regulation. Investigation of the effects of cryophylactic agents on the isolated rat heart at 37 degree C. Identification and antibiotic prophylaxis of high-risk patients in elective colorectal surgery. The present case presented the movement of an intraspinal bullet after a spinal gunshot injury.

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HIV infection and testing among Latino men who have sex with men in the United States: the role of location of birth and other social determinants. Triage of patients for an extended observation period can be performed adequately on the basis of clinical and procedural criteria. Experimental studies: thrombolytic activity and related phenomena. nucleatum, Bacteroides gingivalis, Actinomyces viscosus, and Streptococcus sanguis.

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To compare the performance of three commercially available anti-human epidermal growth factor receptor 2 (HER2) sarotena tablets 25mg ephedrine antibodies in whole-tissue sections and tissue microarrays (TMAs) of a series of gastric tumors. PLGs are composed of assemblages of gene families that are often mutually exclusive, raising the possibility of unique functional identities for each group.

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