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Acarbose

Redocking simulations of two inhibitors, Carbose and casuarine whose complex structures are known, were performed to assure the appropriate docking pose prediction. Safety and efficacy of Carbose in the treatment of diabetes in Chinese patients. The exaggerated and sustained release of glucagon-like peptide-1 (7-36)amide (GLP-1) seen when sucrose was given with Carbose may play a part in the inhibition of gastric emptying.

Other names for this medication:
Acarbose, Precose, Acarbosa, Byetta, Carbose, Diabose, Glucobay, Gluconase, Prandase,

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Carbose is used (with diet only or diet and other medications) to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Carbose works by slowing the action of certain chemicals that break down food to release glucose (sugar) into your blood. Slowing food digestion helps keep blood glucose from rising very high after meals.

Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

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Colonic strictures and epithelial dysplasia are both known risk factors for the occurrence of colorectal cancer in inflammatory bowel disease (IBD) patients. A near-infrared fluorescent aza-bodipy probe for dual-wavelength detection of hydrogen peroxide in living cells. We believe that the miRcomp and miRcompData packages will facilitate the development of new methodology for microRNA expression estimation. Fulminant liver failure from drug ingestion is associated with a high mortality, and the introduction of liver transplantation has improved the mortality significantly if done in a timely fashion.

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Twelve patients were seen before therapy and 12 after treatment elsewhere. A strong test of this hypothesis is to require a computational model of the basal ganglia to generate integrated selection sequences in an autonomous agent, we therefore describe a robot architecture into which such a model is embedded, and require it to control action selection in a robotic task inspired by animal observations.

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Do practice nurses have the knowledge to provide diabetes self-management education? To evaluate the diagnostic accuracy of dynamic contrast-enhanced (DCE) magnetic resonance (MR) and diffusion-weighted imaging (DWI) sequences for defining benignity or malignancy of solitary pulmonary lesions (SPL). Thus, identification of simple parameters which could predict the outcome of HUTT could simplify diagnostic steps by obviating the need for HUTT.

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A classification of the cortical branches of the middle cerebral artery (MCA) is suggested by means of which each branch in any hemisphere can be qualified and identified in any variant of MCA branching. Significantly elevated two- to three-fold risks were observed for men employed in health care, railroad and trolley construction, sheet and plate metal fabrication, and as moving equipment operators. Patients diagnosed with ICH between January 2012 and February 2014 at 50 tertiary and secondary hospitals in China were enrolled into this prospective cohort study.

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EEG manifestations of functional disorders of the central nervous system following irradiation and sympathectomy The extramural vessels reach the wall of the intestine at the mesenteric margin. In addition, 42 plant species belonging to 22 botanical families (Hammada scoparia, Acacia tortilis, Zygophyllum gaetulum, Nucularia perrinii, and Panicum turgidum among the species most used) were listed as used in the treatment of these diseases, as well as about 30 remedies of animal (e.g., from camels, donkeys, and/or spiny-tailed lizards) and mineral origin, and of cauterizations. Central sleep apnea also occurs in number of disorders across all age groups and both genders.

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The KRG-induced inward currents were concentration dependent and were maintained in the presence of tetrodotoxin, a voltage gated Na channel blocker. Key pointsThis study is one of the largest series of soccer related SD with reported 15 cases.In our series, CAD is the most common cause of SCD also in very young athletes in contrast with international literature.In autopsy, detailed cardio-vascular system evaluation and toxicological analysis including doping agents are essential to determine precise cause of exercise induced SD.Medical screening is important for all people interested in sport, not only for athletes, as a powerful means of prevention. In terms of final rehabilitation, however, complications such as corneal oedema, retinal detachment, and cystoid macular oedema remain problematic. VPA was shown to restore or improve responsiveness of tumors to conventional therapeutic agents, to enhance the efficacy of adenoviral gene therapy, to sensitize TRAIL-resistant tumor cells to apoptosis, and to enhance radiosensitivity of tumor cells. The most common cause of illness were respiratory system (60 cases) and the digestive system (27 cases) in the total 233 cases illnesses in the China National Games.

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Tendinitis of the greater trochanter and its treatment with decimeter-band waves and sine-modulated currents Combinations of brain-specific proteins increase the sensitivity and specificity for outcome prediction. Effect of Vaccinium myrtillus anthocyanosides on ischaemia reperfusion injury in hamster cheek pouch microcirculation. The reverse CART technique followed by multiple restenting across the stent struts restored antegrade flow. The intra-acinar arteries became more muscular during childhood as they increased in size.

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This is also the first paper that introduces intelligent algorithm-based UASN routing protocols. Numerical experiments on some brain tumor images highlighted the efficiency and robustness of this method.

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Augmentative communication, evolution, and progress for nonspeaking children. Various investigators have reported that steroids have ulcerogenic properties both in the experimental and clinical situation, while others have reported that steroids will protect against acute ulcer formation.

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Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons. A set of fractions eluting from the column contained three species of apparent molecular masses 175-, 109- and 81 K. More people achieved their energy and protein requirements with the supplement drink intervention with no sufficient impact on habitual food consumption.

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Anti-obesity agents would in theory be beneficial, but have either had limited efficacy or have been avoided because of concern about long-term safety. ILS increased SHBG, although associations with glucose were not significant.

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Effect of fibrinogen split products on the activity of blood coagulation factors II, V, VII, VIII and X in the plasm Professional judgment in complex clinical situations such as the assessment of suicide risk encompasses a multifaceted cognitive understanding of the substantive issues, technical expertise, and emotional awareness. Outcome was assessed using the Glasgow Outcome Scale and by evaluating social behavior, school performance, and vocational functioning. The biological network is among the candidate networks, yet novel designs can be generated.

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This agent has demonstrated encouraging results in both the minimal residual disease setting and the relapsed/refractory setting. After filtering, the hybridization data were normalized and statistically analyzed. This study was conducted to evaluate the clinical performance of the ventricular automatic capture feature as implemented in the Insignia I Ultra pacemaker system (Guidant) utilizing a variety of ventricular leads.

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Reference values of impulse oscillometric lung function indices in adults of advanced age. Clinically and epidemiologically informative data can be extracted from whole-genome sequence data in real time with straightforward, publicly available tools. Step length differential improved significantly more for the COGT. We present a case of vaginal ectopic ureter with ipsilateral partial duplication of the upper ureter (Y-type ureter), ipsilateral hypoplastic pelvic kidney and bicornuate uterus in a 20-year-old woman who presented with mild urinary incontinence since infancy. Water avoidance and repeat restraint stress each led to visceral hyperalgesia, accompanied by mucosal inflammation and impaired mucosal barrier function.

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As expected, a marked reduction of the constitutive as well as of the IFN-gamma or IL-4-driven expression on HLA-DR, HLA-DP and HLA-DQ was observed on IL-10-cultured monocytes. In this paper, we explore recent contributions of NHCs to the study of systematics and biogeography, genomics, morphology, stable isotope ecology, and parasites and pathogens of mammals. IncI1/ST3 and IncN/ST1 plasmids drive the spread of blaTEM-52 and blaCTX-M-1/-32 in diverse Escherichia coli clones from different piggeries. The facilitation was abolished by injection of the specific alpha 1-adrenoceptor antagonist, prazosin (0.5 mg/kg i.v.). The data support the hypothesis that lip repair primarily produces a bone-bending effect on the anterior maxillary alveolus (alveolar molding), accompanied by controlled uprighting of maxillary incisors, and secondarily produces a bone-remodeling effect (bone resorption) in the base of the anterior maxillary alveolus.

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It usually presents in the adolescent age group and is treated primarily by surgery followed by adjuvant chemotherapy. Pathobiology of Pneumocystis pneumonia: life cycle, cell wall and cell signal transduction. Significant proportion of Pacific patients present with late-stage disease. The flow in the adjacent main arteries was not affected, and no systemic symptoms were detected. Some of the new compounds were found to be as potent as prazosin.

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TF can be detected in urine and may reflect the activation state of renal macrophages. Are radiologists responsible for informing patients of the results of needle biopsies of the breast?

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The abnormal metabolism of cortisol by TMPOAG cells may be of significance in the pathogenesis of POAG. To investigate the value of whole body positron emission tomography/computed tomography (PET/CT) in screening for metastatic choroidal melanoma in patients initially diagnosed with choroidal melanoma. Acute myocarditis in a captive African elephant (Loxodonta africana).

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Metabolites from Microcystis aeruginosa bloom material collected at a water reservoir near Kibbutz Hafetz Haim, Israel. Histologic examination demonstrated well preserved morphology in all patches. To study mitochondrial protein age dynamics, we targeted a time-sensitive fluorescent protein, MitoTimer, to the mitochondrial matrix. Treatment outcomes of obstructive sleep apnoea in obese community-dwelling children: the NANOS study.

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Solubilization assays of membrane skeletons were used to study protein interactions inside the skeleton. Thus, while USVs were the most common vocalization type across contexts, the spectrotemporal features of USVs were context-dependent. Glycosylation Status of CD43 Protein Is Associated with Resistance of Leukemia Cells to CTL-Mediated Cytolysis.

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Thyroid hormone activates Akt and prevents serum starvation-induced cell death in neonatal rat cardiomyocytes. Establishing an AG- inventory in a hospital-based blood bank is cost-effective and time-efficient. Two-choice egg count bioassays with Anopheles are best done with a two-tier design that (1) implements a parallel series of experiments with mosquitoes given a choice of two identical substrates choices and, (2) uses a single mosquito in each test cage rather than groups of mosquitoes to assess the preference of a test or control solution. The effect of memory impairment on verbal recognition scores and the marking of acoustic and semantic distractors.

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Total or subtotal resection of the tongue for malignant lesions creates difficult reconstructive problems. By this method, membrane fluidity of PMN, which were treated with membrane fluidizer, was measured successfully. Therefore, we have developed 5 standard sonographic sections enabling detailed study of the brain stem.

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Ulcerogenic activities of the compounds were also studied and no gastrointestinal bleeding was observed at the 100 mg/kg dose level. Stretchable, High-k Dielectric Elastomers through Liquid-Metal Inclusions. In the current study, mutations of JAK2 V617F, JAK2 exon 12, MPL exon 10, and CALR exon 9 were analyzed in 929 Chinese patients with BCR-ABL1-negative MPN, including 234 cases of polycythemia vera (PV), 428 ETs, 187 PMFs, and 80 unclassifiable MPNs (MPN-Us).

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Tuberculin sensitivity in adolescents, high school students in Saransk The aim of this feasibility study is to assess the combination of the multivariate calibration technique of Partial Least-Squares with Raman spectroscopy for the estimation of glucose, lactic acid, and urea concentrations in the presence of each other in a water substrate.

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In 2 of the glioblastomas with EGFR gene amplification, a rearrangement of the gene affecting the extracellular domain of the receptor was identified and DNA sequence analyses revealed an identical deletion-rearrangement of 801 base pairs between exons 2 to 7, resulting in an in-frame fusion of exons 1 and 8. In this study, we examined the role of Epo in prostate cancer (PCa) progression, using in vitro cell culture systems and in vivo bone metastatic assays.

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We included randomised, double-blind, placebo- or active-controlled studies, with at least 10 participants per treatment arm, using naproxen alone or with an antiemetic to treat a migraine headache episode. Leptomeningeal metastasis (LM) results from metastatic spread of cancer to the leptomeninges, giving rise to central nervous system dysfunction. A number of physiological characteristics were studied on some 29 strains of phage-propagating staphylococci belonging to the Basic International Series and the Seto-Wilson bovine-adapted set.

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This cross-sectional study shows that high numbers of postmenopausal women with acromegaly develop vertebral fractures in relation to the activity of disease. Changes in mitral annular shape and size determine the stress exerted on the mitral leaflets and, therefore, the durability of repair. There were 3 patients who had non-union, and 6 patients had delayed union which was treated with dynamization.

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In this study, we used HT29 cells treated with NNK to simulate the long-term exposure of cigarette smoke. Putative oncogene Brachyury (T) is essential to specify cell fate but dispensable for notochord progenitor proliferation and EMT. Being below the age of 12 years and female gender were found to be predictors of low self-esteem in tic disorder. Effect of amrinone infusion on temperature changes in elderly patients undergoing abdominal surgery Noninvasive ICP estimation may be useful in patients at risk of developing intracranial hypertension who require prone positioning.

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The coexistence of these unusual findings led the authors to report this case. This article reviews, discusses, and elaborates considerations and recommendations summarized by the biological research working group at the May 1993 NIMH conference on ethical issues in mental health research on children and adolescents. UTI was administered by intraperitoneal injection immediately following SAH.

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We hypothesize that this hypermobility places abnormal shear force on the vessel, causing intimal injury and dissection. A shelf-sea model of the Bay of Bengal has been used to investigate how the combined effect of sea level rise and changes in other environmental conditions under climate change may alter the frequency of extreme sea level events for the period 1971 to 2099. Fusariosis in a Patient with Acute Myeloid Leukemia: A Case Report and Review of the Literature. Arterial bleeding during EUS-guided pseudocyst drainage stopped by prospectul la clindamycin 600 mg placement of a covered self-expandable metal stent. We selected RCTs or quasi-randomised trials of memory rehabilitation or cognitive rehabilitation for people with MS in which a memory rehabilitation treatment group was compared to a control group.

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The purpose of this study was to clarify the frequency of and risk factors for liver abscess formation prandase hyperglycemia vs hypoglycemia after transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma or metastatic hepatic tumors after undergoing bilioenteric anastomosis. After a 6-month epiretinal implantation in the eyes of rabbits, we found no local retinal toxicity and no mechanical compression caused by the array. In addition, the two species are geographically well separated: D. Under HCV NS5A expression, RNA interference (RNAi) targeting of NS5ATP9 could reverse the inhibition of HepG2 cell proliferation, suggesting that NS5ATP9 might be an anti-proliferation gene that plays an important role in the suppression of cell growth mediated by HCV NS5A via MEK/ERK signaling pathway.

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There is an opinion that encouraging young people to practice sports and promoting a healthy lifestyle through sports and physical recreation could be helpful nateglinide missed dose of levothyroxine in solving this problem. Tooth brushing, tooth wear and dentine hypersensitivity--are they associated? These data indicate that the presence of neurological stimulation signaling vasopressin release may play an important role in promoting neural regeneration of the vasopressinergic component of the neurosecretory system.

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