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Anxinil (Buspirone)

Anxinil is a novel anxiolytic agent unrelated to the benzodiazepines in structure or pharmacologic properties. Extensive clinical studies have shown Anxinil to be effective in the treatment of anxiety, with efficacy comparable to diazepam or clorazepate. Anxinil exhibits a unique pharmacologic profile in that it alleviates anxiety without causing sedation or functional impairment and does not promote abuse or physical dependence. Furthermore, pre-clinical studies have shown that Anxinil does not possess anti-convulsant or muscle relaxant properties and does not interact significantly with central nervous system depressants. Biochemical and electrophysiologic studies indicate that Anxinil alters monoaminergic and GABAergic systems in a manner different from that of the benzodiazepines. The uniform depressant action of the benzodiazepines upon serotonergic, noradrenergic, and dopaminergic cell firing may result from their facilitatory effect on gamma-aminobutyric acid and its known inhibitory influence in these monoaminergic areas. Unlike the benzodiazepines, Anxinil exerts a differential influence upon monoaminergic neuronal activity, suppressing serotonergic activity while enhancing dopaminergic and noradrenergic cell firing. The mechanism of action of Anxinil challenges the notion that only one neurotransmitter mediates anxiety. The interaction with multiple neurotransmitters at multiple brain sites suggests that Anxinil may alter diverse activities within a “neural matrix of anxiety.” In contrast to the benzodiazepines, Anxinil orchestrates activity within this neural matrix to achieve effective treatment of anxiety while preserving arousal and attentional processes.

Other names for this medication:
Buspirone, Buspar, Ansial, Ansitec, Ansiten, Anxinil, Anxiron, Bespar, Busansil, Busirone, Buspin, Buspiron, Buspirona, Ledion, Narol, Neurosine, Paxon, Sorbon, Spamilan, Spitomin,

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Apazol, Rolap, Dolofarmalan, Fabamox, Pantor, Tecta, Myodura, Lanex, Exomax, Sarlo, Moxatag, Neoset, Reloxyl, Baclofen, Cipralex, Fluvin, Famvir, Busirone, Nizagara, Klaxon, Anamet, Tacardia, Clonotril, Lanoxin, Merofex, Tegretol, Zimox, Losartan, Edion, Orfarin, Metrosil, Fenixa, Spectrem, Tandam, Agrixal, Klabet, Xenid, Alprostadil, Nucoxia, Dulane, Laroxyl, Klavax, Indapamide, Fulgram, Pantosec, Bisocor, Pantecta, Indaflex, Claritt,

Anxinil is used to treat certain anxiety disorders or to relieve the symptoms of anxiety. However, Anxinil usually is not used for anxiety or tension caused by the stress of everyday life.

It is not known exactly how Anxinil works to relieve the symptoms of anxiety. Anxinil is thought to work by decreasing the amount and actions of a chemical known as serotonin in certain parts of the brain.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

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Clinical characteristics of such patients, concomitant pathologies, the strategy and extent of cardiosurgical treatment and postoperative therapy are described The original observations are compared with literature data concerning the immediate postoperative outcomes, clinical features, and peculiarities ofsurgical intervention in the patients of this age group. Preoperative regional ejection fraction was normal in 42 of these segments and abnormal in 29.

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