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How Modavigil works to help increase wakefulness and decrease sleepiness isn’t clear. The drug works in the brain to increase amounts of certain chemical messengers such as dopamine. It also seems to affect the messenger glutamate in certain areas of the brain.

These actions may result in stimulation of brain activities, which could make you feel less tired.

How long does it take to work?

Modavigil begins to work within 30 to 60 minutes of when you take it. If you take it with food, the drug might take slightly longer to start working.

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Hydrogeochemical and isotopic tracers for identification of seasonal and long-term over-exploitation of the Pleistocene thermal waters. These findings demonstrated the feasibility of producing biological active rhIGFBP-3 in rice using a transgenic approach, which will definitely encourage more research on the therapeutic use of hIGFBP-3 in future.

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Some neuropathological features were suggestive of amyotrophic lateral sclerosis (ALS), namely Bunina bodies. Our work identifies the Set8-Numb-p53 signaling axis as an important regulatory pathway for apoptosis and suggests a therapeutic strategy by targeting Numb methylation.

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